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emdepth

-- import "github.com/brentp/goleft/emdepth"

emdepth uses a simplified EM algorithm to assign copy-number given a set of depths. it is based off the implementation in cn.mops. Like cn.mops, it works best with more samples and it assumes that most samples will have copy-number 2. emdepth consists of a single function EMDepth that iteratively assigns depths to copy-numbers, adjusts the center of each copy-number bin. and re-assigns... This package does no normalization and therefore expects incoming data to be normalized.